Etude STORM

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Adresse

Rue Gabrielle Perret-Gentil 4
1205 Genève
Suisse

Professeur
Enrico Tessitore
Directeur Centre des cancers
Professeur
Nicolas Mach
Directeur adjoint Centre des cancers

Etude randomisée multicentrique du traitement de récupération des cancers de la prostate oligométastatiques (STORM- trial).

Indication 

Cancer de la prostate oligométastatique 

Phase I/II

Status : ouverte à l'inclusion

Sponsor
Ghent University, Ghent, Belgium - Professor  Piet Ost

Investigateur
Dr Thomas Zilli -
Service de radio-oncologie HUG
Avenue de la Roseraie 53
1205 Genève
Tél. +4122 37 27 132

Consulter le protocole de l'étude >>

 

Objectives

Primary Objective:
-To compare metastases-free survival (MFS) between metastasis-directed therapy and metastasis-directed therapy with whole pelvis radiotherapy for oligorecurrent nodal prostate cancer.
Secondary Objectives:
- To compare clinical progression-free survival between arms
- To compare biochemical progression between arms
- To compare late toxicity between arms
- To compare the quality of life between arms.
- To compare the relapse pattern between arms
- To compare time to start of palliative ADT, time to castration-resistant disease and overall survival between arms
- Economical evaluation of different treatment arms
- Sensitivity and specificity of imaging modality for patients receiving sLND as MDT
- Biomarker discovery: To develop a miRNA panel predictive for treatment response using whole genome miRNA expression profiling.

 

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Dernière mise à jour : 28/07/2020