H5N1 Analysis Request Form : https://www.hug.ch/laboratoire-virologie/centre-national-reference-pour-infections-virales
*Case definition for suspected viral respiratory disease: 1) ARI (inclusion criterion): acute respiratory disease defined as "a disease that begins acutely with cough, sore throat, shortness of breath or cold, and of infectious origin according to the physician's judgement‘. This definition is consistent with the WHO definition of ’Acute Respiratory Infections‘ (ARI). 2) ILI (optional criterion): ’ sudden onset of high fever (>38°C) with cough or sore throat".
For samples that are positive for influenza A and/or B, a detailed characterization of the influenza viruses present in the sample will be performed (subtyping, antigenic proximity to vaccine strains, genotyping and identification of mutations associated with antiviral resistance).
Week 40 of 2025 marked the start of a new season of surveillance for respiratory viruses circulating in the Swiss population. During week 48, 46 samples from patients with symptoms of acute respiratory infection were sent to the CNRI for analysis. The CNRI detected the presence of SARS-CoV-2 in 5 samples, of Influenza A in 13 samples and of RSV in no sample. The circulation of Influenza viruses among the Swiss popilation is starting to increase.

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