H5N1 Analysis Request Form : https://www.hug.ch/laboratoire-virologie/centre-national-reference-pour-infections-virales
*Case definition for suspected viral respiratory disease: 1) ARI (inclusion criterion): acute respiratory disease defined as "a disease that begins acutely with cough, sore throat, shortness of breath or cold, and of infectious origin according to the physician's judgement‘. This definition is consistent with the WHO definition of ’Acute Respiratory Infections‘ (ARI). 2) ILI (optional criterion): ’ sudden onset of high fever (>38°C) with cough or sore throat".
For samples that are positive for influenza A and/or B, a detailed characterization of the influenza viruses present in the sample will be performed (subtyping, antigenic proximity to vaccine strains, genotyping and identification of mutations associated with antiviral resistance).
In calendar week 40 of 2025, a new season of monitoring respiratory viruses circulating among the Swiss population began. In calendar week 49, 53 samples from patients with symptoms of acute respiratory infection were sent to the NRI for analysis. The CNRI detected SARS-CoV-2 in 5 samples, influenza type A in 17 samples and RSV in 2 samples. The spread of the influenza virus among the Swiss population is increasing rapidly.

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