Ethics submission

Titre
Secrétariat
Adresse

Laura Mifano
Switzerland

Titre
Coordinatrice
Adresse

Giannina Rita Iannotti, PhD-PD
Switzerland

Adresse

Centre de médecine virtuelle
Olivier Kannape
Switzerland

Ethics submission

Contenu

The NeuroCentre helps to draft ORH ethics protocols and patient information and consent letters.

It also assists in documents submission of on the BASEC platform.

@neurIST: Integrated biomedical informatics for the management of brain aneurysms
Contenu

Cerebral aneurysms are abnormalities in the blood vessels supplying our brain. Aneurysms are diagnosed by X-ray, CT scan, angiography or MRI. When a brain aneurysm ruptures, treatment of the aneurysm is essential for the patient to survive.

The @neurIST project aims to determine the causes and development of cerebral aneurysms in order to improve their treatment.

Plasma: Investigation of the Plasticity of Deep Brain Structures in Mild Cognitive Impairment and Healthy Aging
Contenu

Memory, learning, time estimation and decision making, which are essential for everyday life, are supported by many brain structures. Cognitive decline is caused by multiple failures in the superficial and deep structures of the brain.

New non-invasive stimulation techniques have the potential to help the brain preserve or even repair certain defective functions. The PlasMA project aims to evaluate the effects of transcranial electrical stimulation on learning and memory.

SMELL-RS: a test-retest reliability study (SARS-CoV-2 patients included)
Contenu

In the presence of a smell disorder, tests are carried out to measure olfactory function and make a diagnosis. However, the results of these tests can be improved, because they are influenced by the individual experience of smells and the genetic code of each person.

The Rhinology and Olfactology Unit seeks to determine the reliability of SMELL-RS, a new universal olfactory test.

STORMM: Middle Meningeal Artery (MMA) Embolization for cSDH: Rationale and Design for the STOp Recurrence of MMA Bleeding (STORMM) randomized-Control Trial
Contenu

With symptomatic subdural haematomas, surgical evacuation of the haematoma is performed in order to avoid severe after-effects and enable the best possible neurological recovery. However, recurrence of these haematomas is often observed.

Recent studies suggest that embolization of the middle meningeal artery (the artery that stimulates this bleeding), in addition to surgical evacuation of the haematoma, would limit the recurrence of the haematoma.

The STORMM project aims to study whether the effectiveness of embolization of the middle meningeal artery in the recurrence of subdural haematomas is good, equivalent or superior to conventional radio-clinical follow-up.

HYPNO-VR: Use of virtual reality to improve perioperative care and in particular the immediate preoperative stress of patients in neurosurgery
Contenu

Nearly half of hospitalized patients suffer from pain. There is considerable evidence that non-pharmacological adjunct techniques, such as cognitive behavioral therapy and relaxation techniques, can reduce pain perception.

Virtual reality is an exciting new technology that offers multiple possibilities for use in the hospital. It allows a complete immersion in a distant virtual place and a total escape, without physical displacement. Its positive effects have been studied since the 90s in pain and anxiety management, neuro-rehabilitation and psychotherapy.

In our study, we want to use virtual reality during the period of sedation induced by anesthesiologists in the preoperative period to measure the beneficial effect on stress, and on the intraoperative and postoperative parameters that follow. By improving the patient's environment at the time of sedation we hope to decrease the effect of the impact of stress and pain on surgery and its complications.

•    BASEC No. 2020-00962
•    Sponsor: HUG
•    Principal investigator: Prof. Karl Schaller, Head of Division, and Dre Insa Janssen, Senior Resident, Division of Neurosurgery

 

Investigation of inappropriate secretion or insufficient secretion of oxytocin after pituitary surgery and its possible behavioural, electrolyte and metabolic effects
Contenu

Oxytocin, in addition to its effect on women during childbirth and breastfeeding, seems to have less known effects including effects on behavior (including confidence), hydro-electrolyte balance (salt), and metabolism (fats).

In this study, we wish to test the hypothesis of a release of oxytocin after pituitary surgery and, if it occurs, try to evaluate the effects of this release on confidence, salt balance and fat metabolism.

•    BASEC No. 2021-01193
•    Sponsor: HUG
•    Principal investigator: Pr Shahan Momjian, Senior Staff Physician, Division of Neurosurgery, and Pre Sophie de Seigneux, Head of Division, Division of Nephrology and Hypertension

 

MRI with DTI and neurophysiology with motor evoked potentials and somatosensory in patients with cervical spondylotic myelopathy: how to identify the best responders to surgical treatment
Contenu

Degenerative disorders of the cervical spine are common causes of myelopathy, especially in patients over 40 years of age.

The purpose of this study is to monitor regularly and with standardized means all patients operated on for cervical myelopathy in the Neurosurgery Department of HUG in order to better understand, diagnose and treat the disease, and to identify patients respond best to surgical treatment.

•    BASEC No. 2018-00122
•    Sponsor: HUG
•    Principal investigator: Prof. Enrico Tessitore, Senior Staff Physician, Division of Neurosurgery
 

EUROSPIN: The EUropean RObotic SPinal Instrumentation Trial
Contenu

EUROSPIN is an observational study taking place in several European hospitals in Austria, Germany, France, the Netherlands and Switzerland.

The purpose of this study is to compare, in patients requiring fixation of the spine with pedicle screws, three different techniques to assist with screw insertion: 1) traditional surgery to fix pedicle screws using x-ray control, 2) navigated surgery using a camera and a frame of reference attached to the patient, and 3) robot-assisted surgery.

•    BASEC No. 2019-00901
•    Sponsor: Bergman Clinics, Amsterdam, The Netherlands.
•    Principal investigator: Pr Enrico Tessitore, Senior staff physician, et Dr Granit Molliqaj, Senior resident, Division of Neurosurgery

Last update : 03/04/2023

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