Forschung

Principal investigator
Marie Cohen, PhD 
Tel : +41223724381

Das Team interessiert sich für die Entwicklung neuer Marker und Behandlungen für invasive Trophoblasten Erkrankungen. Zur Forschungsgruppe: Laboratory of Gynaecological Tumor and Development Biology

• Cohen M, Wuillemin C, Irion O, Bischof P. Regulation of MMP-9 by p53 in first trimester cytotrophoblastic cells. Hum Reprod 2008, 23, 2273-81
• Cohen M, Wuillemin C, Bischof P. Trophoblastic p53 is stabilised by a cis-trans isomerisation necessary for the formation of high molecular weight complexes involving the N-terminus part of p53. Biochimie 2008, 90, 855-862. 
• Cohen M, Wuillemin C, Chai SY, Bischof P. Effects of ligands or substrate of insulin-regulated aminopeptidase (IRAP) on trophoblast invasion. J Peptide Sci 2008, 14, 883-887.
• Li L, Cohen M, Sow MH, Wu JY, Branka N, Bischof P and Irminger-Finger I. Expression and function of BARD1 splice variants in human trophoblast. Int J Biochem Cell Biol 2007, 39, 1659-1672.
• Cohen M, Bischof P. Factors regulating trophoblast invasion. Gynecologic and Obstetric Investigation 2007, 64, 126-129.
• Cohen M, Meisser A, Haenggeli L, Irminger-Finger I, Bischof P. Status of p53 in cytotophoblastic cells. Molecular Human Reproduction 2007, 13, 111-6.
• Cohen M, Meisser A, Bischof P. Metalloproteinases and human placental invasiveness. Placenta 2006, 27, 783-93.
• Cohen M, Meisser A, Haenggeli L, Bischof P. Involvement of MAPK pathway induced MMP-9 expression in human trophoblastic cells. Mol Hum Reprod?in TNF- 2006, 12, 225-32.
• Meisser A, Cohen M, Bischof P. Concentrations of circulating gelatinases (Matrix Metalloproteinase-2 and -9) are dependent on the conditions of blood collection. Clinical chemistry 2005, 51, 274-6.